Cognitive inhibition and thought disorder in schizophrenia.

Full Abstract

In schizophrenia, inhibitory control is reported to be disturbed and has been associated with formal thought disorder (TD). The negative priming task (NP) is used as a measure for inhibition; however, controversial results are found in the literature. The aim of this study was to evaluate cognitive inhibition in schizophrenia and TD. Additionally, the influence of the course of disease and of medication were evaluated. The NP was used to compare TD patients (n = 17) with non-TD (n = 19) and healthy controls (n = 21). Results showed similar performance among TD and non-TD patients, and controls. No influence of the course of disease or medication was found. Our results are in line with recent studies, where patients, irrespective of TD, show normal performance in the NP.Copyright 2003 S. Karger AG, Basel

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Author information

Author/s: Roesch-Ely, Daniela (D); Spitzer, Manfred (M); Weisbrod, Matthias (M);

Affiliation: Department of Psychiatry, University of Heidelberg, Heidelberg, Germany. daniela_roesch(-atsign-)med.uni-heidelberg.de

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal: Psychopathology (Psychopathology), published in Switzerland. (Language: eng)

Reference: -2003 Jan-Feb; vol 36 (issue 1) : pp 23-32

Dates: Created 2003/04/07; Completed 2003/08/19; Revised 2006/11/15;

PMID: 12679589, status: MEDLINE (last retrieval date: 12/26/2008)

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adult
Analysis of Variance
Antipsychotic Agents - therapeutic use
Brief Psychiatric Rating Scale
Cognition Disorders - diagnosis; etiology
Female
Humans

Humans
Inhibition (Psychology)
Male
Neuropsychological Tests
Reaction Time
Schizophrenia - complications; drug therapy
Thinking

Associated Chemicals: Antipsychotic Agents (0)

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