Research article summary:

Attentional mechanisms of borderline personality disorder.

Abstract Extract:
We consider whether disruption of a specific neural circuit related to self-regulation is an underlying biological deficit in borderline personality disorder (BPD). Because patients with BPD exhibit a poor ability to regulate negative affect, we ... (Full abstract text below)

Published 2002Dec in Journal: Proc Natl Acad Sci U S A (Language : eng)

Full Pubmed Extract

This information was retrieved, real-time, on your behalf from the public area of the Pubmed website:

1. Proc Natl Acad Sci U S A. 2002 Dec;99(25):16366-70

Attentional mechanisms of borderline personality disorder.

Posner MI, Rothbart MK, Vizueta N, Levy KN, Evans DE, Thomas KM, Clarkin JF

Sackler Institute for Developmental Psychobiology, Weill Medical College of Cornell University, New York, NY 10021, USA. mip2003@med.cornell.edu

We consider whether disruption of a specific neural circuit related to self-regulation is an underlying biological deficit in borderline personality disorder (BPD). Because patients with BPD exhibit a poor ability to regulate negative affect, we hypothesized that brain mechanisms thought to be involved in such self-regulation would function abnormally even in situations that seem remote from the symptoms exhibited by these patients. To test this idea, we compared the efficiency of attentional networks in BPD patients with controls who were matched to the patients in having very low self-reported effortful control and very high negative emotionality and controls who were average in these two temperamental dimensions. We found that the patients exhibited significantly greater difficulty in their ability to resolve conflict among stimulus dimensions in a purely cognitive task than did average controls but displayed no deficit in overall reaction time, errors, or other attentional networks. The temperamentally matched group did not differ significantly from either group. A significant correlation was found between measures of the ability to control conflict in the reaction-time task and self-reported effortful control.

PMID : 12456876 [PubMed - Indexed for MEDLINE]

This information is obtained from the National Library of Medicine (NLM). Abstract text and other information may be subject to copyright. Type "NLM copyright" into Google for more information.

Full Author Information

First Name	LastName	Initials
Michael I	Posner	MI
Mary K	Rothbart	MK
Nathalie	Vizueta	N
Kenneth N	Levy	KN
David E	Evans	DE
Kathleen M	Thomas	KM
John F	Clarkin	JF

Affiliation: Sackler Institute for Developmental Psychobiology, Weill Medical College of Cornell University, New York, NY 10021, USA. mip2003@med.cornell.edu

3rd Party provider links

Click the links below to go to related 3rd party information:

MESH categories and related page links

This article was linked to the MESH categories shown on the left below. The links on the right are related Memletics pages.

Links for this article

For links to places where you can get the full text of this article see links. Note there may be a subscription or fee required for access to the full text.

New! Using similar technology to this site, we have launched find-health-articles.com, targeting over 1 million health research article abstracts.

Here are some articles related to this one (by title keywords):

Effective treatments of school-aged conduct disordered children: recommendations for changing clinical and research practices.

Date violence and date rape among adolescents: associations with disordered eating behaviors and psychological health.

A study of parents of violent children.

Personality and the goal-striving process: the influence of achievement goal patterns, goal level, and mental focus on performance and enjoyment.

Divided and selective attention in panic disorder. A comparative study of patients with panic disorder, major depression and healthy controls.

The structure of schizotypy: relationships between neurocognitive and personality disorder features in relatives of schizophrenic patients in the UCLA Family Study.

The role of optimism in the process of schema-focused cognitive therapy of personality problems.

Personality dimensions and neuropsychological performance in first-degree relatives of patients with schizophrenia and affective psychosis.

Executive function profile of children with attention deficit hyperactivity disorder.

Big five dimensions and ADHD symptoms: links between personality traits and clinical symptoms.

>>> Get more research article abstracts like these, or browse abstracts.

Keywords in this article:

ability, abnormally, affect, attentional, average, biological, borderline, bpd, brain, circuit, cognitive, compared, conflict, consider, controls, correlation, deficit, differ, difficulty, dimensions, disorder, displayed, disruption, efficiency, effortful, emotionality, errors, even, exhibit, exhibited, function, greater, group, high, hypothesized, idea, involved, low, matched, measures, mechanisms, negative, networks, neural, not, other, patients, personality, poor, purely, reaction, regulate, regulation, related, remote, reported, resolve, self, significant, situations, specific, stimulus, symptoms, task, temperamental, temperamentally, test, thought, time, underlying, whether, who

Also, see our new free speed reading online course (beta version)